RESET PLATFORM
Junevity RESET is the first siRNA cell reprogramming platform, leveraging human data, machine learning, and siRNA.
Transcriptional dysregulation drives disease
PROBLEM
Diseases related to longevity and aging see profound transcriptional dysregulation, which is often overlooked in drug discovery due to its complexity.
Cell Reprogramming
SOLUTION
Dr. Janine Sengstack was the first to show that repressing a single transcription can reprogram gene expression to healthy state in her work at UCSF.
Junevity builds on this approach. We identify pathways that become overactive with age and disease. Then, we develop safe siRNA therapeutics to reprogram these pathways, resetting cell health and reversing disease.
This approach unlocks new therapeutics for many diseases related to longevity and aging.
RESET Platform
HOW WE DO IT
RESET is a therapeutic discovery platform combining human omics, genetic linkages, machine learning, a modern wet lab, and siRNA.
Our first-of-its-kind platform enables safe siRNA therapeutics supported by genetic evidence.
